Static & Dynamic Bifurcation Analysis Of a Coupled Acetylcholinesterase / Choline Acetylcholinesterase Enzymes Neurocycle

Document Type : Original Article

Authors

Abstract

Abstract:
Bifurcation and Chaotic behavior of an acetylcholinesterase phemonenological two
compartment model has been studied. Using Garhyan P. and Elnashaie S.S. model [1],This
model describes the cholinergic neurocycle in simple form of two enzyme / two
compartments. In this investigation a more realastic kinetic expression for choline
acetyltransferase has been used. The bifurcation, instability and Chaotic behavior are
investigated with special emphasis on neural transmission in the human brain. This type of
work may be help to stimulate new research directions on brain diseases such as Al zheimer's
and Parkinson diseases.

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